Aspirin

Aspirin for prevention of cardiovascular disease and stroke, U.S. Preventive Services Task Force (USPSTF) (1):

Ideal dose of aspirin:

According to the USPSTF, the ideal dose of aspirin is not known, but a dose of 75 mg per day appears as effective as higher doses and may have less risk of gastrointestinal bleeding.

The USPSTF recommendation for prevention of cardiovascular disease in men:

Men younger than 45 years: For myocardial infarction prevention in men younger than 45 years the USPSTF recommends against the use of aspirin since the benefit for prevention of cardiovascular events are small.

Men age 45 to 79 years: The USPSTF strongly recommends the use of aspirin when the potential benefit due to a reduction in myocardial infarctions is more beneficial than the potential harm due to gastrointestinal hemorrhage.