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Asthma Natural Supplements for Adults with Allergies Plus Much More

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Asthma Natural Supplements For Adults With Allergies

Introduction: Asthma Natural Supplements For Adults With Allergies

Asthma natural supplements for adults with allergies are not typically useful for acute attacks but can help control the inflammation of the airways over the long term. The symptoms which natural supplements might improve include chronic wheezing, shortness of breath, chest tightness and coughing. Asthma symptoms may be provoked by allergens (pollen, pets, chemicals, dust, mold), medications such (aspirin, non-steroidal anti-inflammatory drugs), exercise, upper respiratory infections, stress, smoke, cold air, allergic rhinitis and gastroesophageal reflux. An asthma emergency is characterized by extreme difficulty breathing, blue lips, using upper neck or chest muscles to breath, anxiety from difficulty breathing, fast heart rate, sweating, and confusion. If any these life threatening symptoms occur, one should seek emergency medical care. In this case, asthma natural supplements for adults with allergies would not be useful.

Combining Natural Therapies with Asthma Medications:

Medications should be continued as previously according to the physician treatment plan and should not be changed based on the information contained here. These preventive medicine options may be added in addition to medication under supervision and approval of a physician. If these prevention options lead to improvement in lung function, the physician may then consider adjusting the medications used in the treatment plan.

Vitamin C Used as an Asthma Natural Supplement

Vitamin C may protect against asthma symptoms in adults. Vitamin C resulted in a protective effect against the development of respiratory symptoms in a study of 2,526 adults patients between 1971 and 1972. This study evaluated vitamin C intake and lung (pulmonary) function using forced expiratory volume in 1 second (FEV1), an important measure performance of lung function by amount of air movement within 1 second . After adjusting for variables, dietary vitamin C intake was positively and significantly associated with the level of FEV1. Those consuming an average of vitamin C of 17 mg/day, 66 mg/day, or 128 mg/day had average FEV1 values of about 2530 ml, 2550 ml, 2570 ml, respectively. The authors conclude that vitamin C has a protective effect on lung function. This beneficial effect was not restricted to just smokers. Vitamin C intake appears to benefit patients with asthma and bronchitis. (1)

A higher vitamin C intake in the diet was associated with a better lung function in asthmatic adults. Britton and colleage studied the association between vitamin C and E on lung function in a study involving 2,633 subjects aged 17-70 years old. The authors found that a higher intake of vitamin C was associated with a higher forced expiratory volume in 1 second (FEV1), an important measure performance of lung function measuring amount of air movement within 1 second and a higher forced vital capacity (FVC), a measure of the strength of lung muscles by measuring the maximum amount of air a person can expel from the lungs. An increase in vitamin C of 40mg/d was associated with a significant increase in FEV1 and FVC of 25.0 ml and 23.3 ml, respectively. An increase in vitamin E of 2.2mg was also associated with increase in FEVI and FVC of 20.1 ml and 23.1 ml. The authors concluded that much of the beneficial effect is due to vitamin C. (2)

Vitamin C and Asthma in Children:

Citrus and kiwi fruit intake was associated with less wheezing, shortness of breath, and cough in children with and without asthma.  The study, which followed 18,737 children living in Central and Northern Italy, found that those eating the most citrus and kiwifruit (5-7 servings per week) had 44% less incidence of wheezing compared to children eating the least (less than once a week). Shortness of breath was reduced by 32%, severe wheeze by 41%, night time cough by 27%, chronic cough by 25%, and runny nose by 28%. In children aged 6–7?yrs, those who ate at least 5 serving of fruit rich in vitamin C per week were less likely to have respiratory-related health problems including wheezing, shortness of breath, or night coughing compared with those who never ate fruit. Children who had asthma when the study began appeared to benefit the most, and protective effects were evident even among children who ate fruit only once or twice a week. (3)

Another study by F. Forastiere et al found that children who consume vitamin C-rich fruit are less likely to experience wheezing—a breathing disorder associated with asthma. In this study, children (n=18,737; 6-7 years old) who ate kiwi or citrus fruits 5 to 7 times a week were about 30% less likely than other children who ate fruit less than once a week to suffer from wheezing (odds ratio [OR]=0.68), chronic coughing (OR=0.75), nighttime coughing (OR=0.73), or non-coryzal rhinitis (OR=0.72). The beneficial effect of vitamin C rich fruit was seen even in children with fruit consumption of only 1 to 2 times per week. Fruit consumption appeared to be most beneficial among children who already had asthma. Asthmatics who ate fruit once a week had a 1-year occurrence of wheeze of 29.3% compared with 47.1% for asthmatic children who ate fruit less than once a week. (4)

A study did not find a link to vitamin C levels in the blood but instead fresh fruits, green vegetables, and salad was associated with better lung function in children. In the cross-sectional study of 2,650 children aged 8-11 years old in the UK, Cook and colleagues reported that a better forced expiratory volume in 1 second (FEV1), a measure of lung function, was positively linked with the frequency of fresh fruits, green vegetables, and salad consumption but was not associated with blood vitamin C levels. The beneficial effect was stronger from fruit consumption than vegetables and salads. Compared to children who never ate fresh fruit, those who ate fresh fruit more than once a day had a 79 ml or 4.3% lower FEV1 value. This link between FEV1 and fruit intake was stronger in children with wheeze than those without. (5)

Yoga and Asthma

Yoga improved weekly number of attacks, peak flow and drug treatment scores in asthma patients. Fifty three patients with asthma underwent training for two weeks in an integrated set of yoga exercises, including breathing exercises, suryanamaskar, yogasana (physical postures), pranayama (breath slowing techniques), dhyana (meditation), and a devotional session, and were told to practise these exercises for 65 minutes daily. They were then compared with a control group of 53 patients with asthma matched for age, sex, and type and severity of asthma, who continued to take their usual drugs. There was a significantly greater improvement in the group who practiced yoga in the weekly number of attacks of asthma, scores for drug treatment, and peak flow rate. This study shows the efficacy of yoga in the long term management of bronchial asthma, but the physiological basis for this beneficial effect needs to be examined in more detail. (6)

A study by Singh V et al showed that yoga breathing had positive effects in 18 patients with mild asthma. Participants were asked to breath using a machine that slowed their breathing similar to that achieved in pranayama yoga or to placebo device. This study demonstrated an improvement in the measured breathing parameters of all patients. It also showed a statistically significant increase in the dose of histamine needed to cause a 20% reduction in average forced expiratory volume in 1 s (FEV1 which is the maximum amount of air you can forcefully exhale in one second) during pranayam (but not in placebo device), demonstrating a tendency towards reduction in allergic asthma symptoms. (7)

Caffeine and Asthma:

Caffeine at a dose of 7 mg/kg was reported to improve lung function in a study that included 10 individuals with bronchial asthma. Patients were given placebo and caffeine (3.5 mg/kg and 7 mg/kg ) two hours prior to exercise and a lung function test (spirometry) was administered an hour and two hours after and at 5, 15, and 30 minutes post exercise. Forced expiratory volume (FEV1), a measure of lung function, improved significantly and stopped constriction of the airways in the lungs caused by exercise. (8)

A review by Welsh EJ et al examined seven available clinical trials on caffeine in asthma, specifically on caffeine\’s effect on lung function tests. Of the 55 asthmatics in these studies, some were given caffeine and others were given placebos. The results showed that even small amounts of caffeine (< 5mg/kg body weight) helps asthmatics breathe more easily for 2 to 4 hours after ingestion. Forced expiratory volume (FEV1), a measure of lung function, showed a small mean improvement of 5% up to 2 hours after consumption of caffeine. In 2 separate studies mean FEV1 improvement were reported at 12% and 18% after caffeine. Another clinical trial looked at the effect of caffeine on exhaled nitric oxide levels and found that there is no significant effect. (9)

Pycnogenol Used as an Asthma Natural Supplement

Pycnogenol may be one of the most useful asthma natural supplements for adults with allergies. Compared to placebo, individuals suffering from asthma (n=22) had better symptom response with use of Pycnogenol (1 mg/lb/day (maximum 200 mg/day)) which significantly reduced leukotrienes (molecules that cause inflammation). Average forced expiratory volume in 1 second (FEV1, volume of air expired in the first second during maximum expiratory effort) or a test of lung function after Pycnogenol significantly increased from baseline (59.6%) by 11% (vs a 4% increase for placebo). Average values of the FEV1/FVC (this number represents the percent of the lung size (FVC) that can be exhaled in 1 second) for Pycnogenol significantly improved to 73.2% (compared to 63.6% at baseline and 65.6% for placebo). Changes from baseline associated with placebo were not significant, but Pycnogenol was significantly better than placebo. (15)

Pycnogenol, French maritime pine bark extract, may be useful in the management of childhood asthma. The research included 60 participants, 6-18 years old, with mild to moderate asthma, who were randomly administered or placebo. After 3 months, researchers determined that those taking Pycnogenol had significantly more improvement in lung function and asthma symptoms, the need for a rescue inhaler, levels of leukotrienes and improved peak expiratory flow (compared to study members assigned to a placebo). (16)

Belcaro G, et al compared a group of patients taking inhaled steroids to a group taking inhaled steroids plus Pycnogenol. The Pycnogenol group was noted to have the following positive findings. 55% of the Pycnogenol group were able to reduce the amount of inhaled steroids needed to control their asthma. Cough, wheezing and difficulty breathing improved significantly only in the Pycnogenol group. Only 6% of the group using inhaled steroids alone were able to reduce the amount of the medication.  There were no serious adverse reactions of Pycnogenol reported in the study (18).

Exercise Induced Asthma:

Preventing exercise induced asthma symptoms prior to exercise: In adults and children with asthma, taking inhaled short and long acting beta2-agonists (such as albuterol, salmeterol, formoterol) before vigourous activity or exercise may prevent exercise induced asthma (EIB), in about 80% of patients. The benefits of treatment may last for 2-3 hours for short action beta agonist or up to 12 hours if long action beta agonists are used. Additionally, a warm-up period prior to exercise is associated with a lesser degree of EIB. In cold weather, a mask or scarf over the mouth may lessen the effects of cold-induced EIB. Children suffering from EIB should not be excluded from sports and other activities but teachers and coaches should be notified that the child suffers from EIB and may need inhaled medication prior to participation. If symptoms of EIB occur during usual non-vigorous play activities, this may an sign of poorly managed or persistent asthma and long-term treatment may be necessary. Appropriate long-term management may reduce EIB. (10)

Effect of asthma medications during rest and exercise: Bronchodilators, including methylxanthines (such as theophylline), sympathomimetic agents (such as albuterol), cromolyn sodium, and corticosteroids increase exercise capacity in patients with limited bronchospasm. During rest and exercise, methylxanthines and sympathomimetic agents increase or have no effect on heart rate and blood pressure. Sympathomimetic agents may also increase blood pressure during rest and exercise. Cromolyn sodium and corticosteroids have no effect on either heart rate or blood pressure during rest and exercise. (11).

A Multi-nutrient Used as an Asthma Natural Supplement

The effects of a 2-month multi-nutrient supplement therapy on oxidative stress was measured by a reduction in malondialdehyde (MDA) levels. Immune response, pulmonary (lung) function, and quality of life was also followed in 30 patients (9 men and 21 women, mean age 38 y) with mild to moderate allergic asthma. Participants received daily dietary supplements of : (a) Green barley powder (15g); (b) Oxy Rich (coenzyme Q10 [90 mg], vitamins A [3,000 IU], C [60 mg], E [22.5 IU], and B6 [6mg]); (c) Omega Rich (vitamin E [9.0 IU], EPA [990 mg], DHA, [660 mg]); (d) Prime C Complex (ascorbic acid/calcium ascorbate [1500 mg]); (e) Bio Shield (green tea extract [336 mg], grape seed extract [75 mg], citrus bioflavonoid complex [54 mg], calcium [165 mg], zinc [15 mg], selenium [150 μg], and vitamins A [15,000 IU], C [246 mg], E [80.6 IU]); and (f) Health Life (vitamins A [6,000 IU], B1 [4.2 mg], B2 [4.5 mg], B3 [60 mg], B6 [6 mg], B12 [9 μg], C [225 mg], D3 [7.5 μg], E [30 mg], biotin [450 μg], panthenic acid [15 mg], folic acid [900 μg], choline [45 mg], inositol [75 mg], selenium [150 μg] zinc [24 mg], magnesium [300 mg], copper [3 mg], calcium [450 mg], chromium [150 μg], and lycopene [3 mg]). During the study period, asthmatics showed non-significantly increased pulmonary function and a trend toward lower IgE levels, a reduction in malondialdehyde (MDA) (a measure of oxidative stress), copper, hs-CRP (an inflammation marker), and CD19 (B lymphocytes which produce antibodies), and increases in levels of selenium, zinc, β-carotene, vitamins C and E, and enzymatic antioxidant activities. Asthma control improved according to a 5 question assessment. Comparing the control of asthma before the study, after the study there were 13 fewer patients poorly controlled, there were 10 more patients partially controlled and there were 3 more patients which became well controlled. A nonsignificant improvement was seen in FVC, FEV1 and FEV1/FVC. The health-related quality-of-life scores of the subjects increased significantly by the end of the study. The results suggest that among patients with mild to moderate allergic asthma nutritional supplement therapy may improve oxidant and antioxidant status, inflammation and immune responses, pulmonary function, and health-related quality of life. There was no placebo group in this study. (12)

Asthma and Diet for Asthma Control:

Asthma and a vegetarian diet: A study looked at diet, lifestyle and disease in 1976 with 27,766 participants, of which 15,228 (55%) were vegetarians. Among female participants, researchers found a higher rate of reported overnight hospitalizations and surgeries among non-vegetarian females compared to vegetarian females. Non-vegetarian males reported more overnight hospitalizations and x-rays. When comparing the rates of disease between non-vegetarian and vegetarians, non-vegetarian females were 1.3 times more likely to report a chemical allergy, 1.2 times more likely to report asthma, 1.17 times more likely to report drug allergy, 1.17 times more likely to report bee-sting allergy, 1.15 times more likely to report hay-fever. Among non-vegetarian males, they were more likely to report chemical and drug allergy. Additionally, use of medication increased by 70-115% in non-vegetarian females and more than doubled in non-vegetarian males. (13)

Possible Prevention Of Asthma By Diet In Children

An analysis of 1,253 children and their mother’s diet while pregnant found that there were lower occurrences of asthma and allergic disease in children whose mothers had higher intake of apples and fish during pregnancy. Compared with children of mothers eating the least amount of apples, children of women in the highest tertile of apple consumption during pregnancy had a 27% risk reduction from wheezing, 46% risk reduction from asthma, and 18% reduction in doctor-confirmed asthma. Maternal fish consumption was associated with a 43% reduction in doctor-confirmed eczema. (17)

Butterbur as an Asthma Natural Supplement For Adults With Allergies

Butterbur is an herbal treatment and is one of the most useful asthma natural supplements for adults with allergies. Butterbur may improve lung function in asthma. Butterbur (Petasites hybridus) root powder is a supplement that contains petasins, a group of anti-inflammatory compounds. In a German prospective, non-randomized, open trial, 80 asthma sufferers (64 adults and 16 children/adolescents) who took 50 mg butterbur extract (Petadolex manufactured by Weber & Weber in Inning, Germany) 3 times a day (children: 50-150 mg daily, depending on age) saw the number, duration, and severity of their asthma attacks decrease during an eight-week study period. During the first two months the patients were treated with the extract, followed by two months during which the intake of the extract was optional. Patients were permitted to continue with their regular asthma medications for the entire duration of the study. At the end of the study, measure of lung function (peak flow, forced expiratory volume [FEV1]) and asthma medication use improved.  The average improvement for peak flow was 28.5% and for FEV1 it was 11.3%. Of the patients taking inhaled asthma medication in addition to butterbur extract, 43% reduced the amount of medication used while they were taking butterbur extract. The study authors speculated that butterbur extract might be effective both as a stand-alone asthma treatment and in combination with other asthma medications. The weakness of the study was that it was not blinded, randomized, and was done by the manufacturer of the product. (14)

Chocolate as an Asthma Natural Supplement

It has been a established that cocoa and chocolate has significant effect on lung function due to the theobromine and theophylline content. Simons FE et al found that an average dose of 468 mg of theobromine and an average dose of 249 mg of theophylline each separately promoted significant improvements in all pulmonary function tests with the effects peaking in about 2 hours and continued lasting improvement in lung function at 6 hours (19). It was apparent on the plotting of serum concentrations that these components remained in the serum for at least several hours longer (19). 468 mg of theobromine is equivalent to about 50 grams of a dark chocolate bar containing 70-90% cocoa (standard chocolate bars contain 100 grams of dark chocolate). Dark chocolate is less palatable than milk chocolate, but contains much more theobromine per given amount of fat content. Cocoa powder may also be mixed into a drink or used in a recipe of choice. Chocolate and cocoa is also known to act as a cough suppressant (20).

Chocolate contains caffeine. Caffeine intake up to 300 mg per day is generally safe for healthy adults. Older patients or those with hypertension, cardiovascular disease, or cerebrovascular disease should avoid more than 1-2 cups of caffeinated beverages per day (no more than 100-200 mg of cafeine intake per day). One cup of coffee contains on average, about 100 mg of caffeine. Each standard sized milk chocolate bar such as Hershey’s contains about 10 mg of caffeine, and each standard size dark chocolate bar contains about 31 mg of caffeine. Standard caffeine intake is generally recognized as safe by the FDA and AMA but can be dangerous with adverse effects such as high bp, stroke, and arrythmias reported. If more than 1-2 cups of caffeinated beverages are consumed per day, it is prudent to seek physician and/or pharmacist approval of caffeine consumption with any medications or supplements. Cocoa and chocolate also contains theobromine which is known to act as a stimulant, vasodilator, and diuretic (21). Theobromine and cocoa may intensify the blood pressure lowering effects of any blood pressure medications.

Choline for an Asthma Natural Supplement

Asthma natural supplements for adults with allergies include choline. Gupta and Gaur evaluated choline for its effect upon control of asthma. There were 3 adult groups tested which included a placebo group, a group taking 500 mg of choline, and a group taking 1000 mg of choline. There was statistically significant improvement in multiple asthma parameters with the greatest improvement seen in the choline group on the higher dose. Choline was noted to improve the following asthma parameters: There was a statistically significant decrease in asthma medications for the high dose choline group. There were less frequent asthma symptoms and more days without symptoms in both choline groups. The authors expressed that choline is a promising preventive agent for asthma and that further confirmation studies should be done. (22)

Omega-3 Fatty Acids and Asthma Control

Omega 3 fish oil is one of the well known asthma natural supplements for adults with allergies. Yang H et al performed a meta analysis and systematic review of omega-3 fatty acid consumption and their relationship to asthma. Studies suggest that both consumption of fish containing omega-3 fatty acids, and supplementing with omega-3 fatty acids found in fish oil may reduce the risk of asthma possibly as high as 30%, but research is not conclusive at this point and requires further investigation. Consumption of fish with omega 3 fatty acids and supplements containing fish oil appears to have more benefits than risk, and is worthwhile to see if it makes a difference in symptoms of asthma.(23)

Children are not advised to use omega-3 fatty acids for this purpose, and it would be more safe in children to increase omega-fatty acids with cold water fish consumption.

Omega-3 Fish Oil for Asthma Adverse Reactions and Interactions:

 

Conclusion: Asthma Natural Supplements For Adults With Allergies

 

References for Asthma Natural Supplements for Adults With Allergies

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