Choline

Choline and asthma:

High dose vs low dose choline: Choline, an essential nutrient, was found to benefit individuals with bronchial asthma after 4 months of taking either low dose choline (500 mg TDS) or high dose choline (1 g TDS). Reduction in asthma symptoms and an increase in the number of days without symptoms were reported by those receiving choline or placebo. These improvements however were only significant in the 2 groups taking choline. Airway improvement and reduction in need to use asthma medication were significant only in the high dose choline group. (2)

A 3-month study that examined the effectiveness of disodium cromoglycate (DSCG, an anti-inflammatory drug) versus choline (an essential nutrient with anti-inflammatory properties) versus placebo (bronchodilators only) for asthma found clinically significant decreases in the severity of symptoms, number of symptomatic days, and the need to use bronchodilators in patients with asthma in study participants taking choline. However, all participants showed some improvement. (3)