Naturally derived topical gel in chronic venous insufficiency (CVI): The effectiveness of aescin (or escin, an extract of horse chestnut), and essential phospholipids (AEPL) gel on the microcirculation was tested by measuring transcutaneous skin PO2 and PCO2 in subjects with chronic venous insufficiency (CVI), venous hypertension (CVH, high pressure in the veins of the legs). The results reveal that treatment with AEPL in the areas of disease of blood vessels is effective in improving skin perfusion (restoring microcirculatory blood flow) and nutrition and prevents venous ulcerations (ulcers that develop on the skin due to improper blood flow). (6)
