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Cirrosis and Vitamin Deficiency
Assessment and Plan: Cirrhosis and Vitamin deficiency
Lévy S, et al found that alcoholics as well as patients with cirrhosis had a high incidence of thiamine deficiency recommended by the authors to give a thiamine supplement to both alcoholic patients and those with cirrhosis related to any cause (1).
In a report by Baines, M. et al oral thiamine at a dose of 250mg for 5 days was as effective as IV thiamine in restoring thiamine levels in alcoholic patients without encephalopathy (2).
Peres WA, et al found a high prevalence of vitamin A deficiency (3), and Lim, LY and Chalasani, N. et al found that a large number of cirrhosis patients were vitamin D deficient (4).
Saja MF documented that vitamin K is often administered in an attempt to correct coagulopathy, but did not result in significant correction of coagulation factors (5).
Muro, N et al showed that Vitamin B12 was often high in cirrhosis patients, and that plasma folic acid levels were shown to be low in cirrhosis patients and even lower if cirrhosis was related to alcohol compared to controls (6).
