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Coffee
Coffee consumption and colorectal cancer:
Highest vs lowest coffee intakes and colon cancer: In a meta-analysis, authors identified 25 case control and 16 cohort studies related to coffee consumption and colorectal cancer risk. Results from case control studies comparing the highest versus the lowest/non category of coffee consumption showed a significant reduction in colorectal cancer (15% risk reduction) and colon cancer (21% risk reduction), but not rectal cancer (5% risk reduction). For cohort studies, risk of colorectal cancer, colon cancer, and rectal cancer were reduced by 6%, 7%, and 2%, respectively. In subgroup analyses using case–control studies, significant inverse associations were found in females for colorectal cancer and in Europe for colorectal and colon cancer, while the subgroup analyses of cohort studies found that coffee drinks substantially decreased risk of colon cancer only in Asian women. (1)