According to Dahmer and Scott, hawthorne was considered safe to take with standard heart failure medications (such as ACE inhibitors, vasodilators, cardiac glycosides), but patients should be careful when taking other herbal supplements that have cardiovascular effects such as danshen, epimedium, ginger, Panax ginseng, turmeric, and valerian (3).
This agent was safe at a dose of 900 mg per day for 2 years when combined with diuretics, ACE inhibitors, beta blockers, glycosides, and aldosterone blockers (4). Hawthorne extract was well tolerated (3,5).
Coenzyme Q10 and congestive heart failure (CHF):
Low levels of coenzyme Q10 have been linked with heart failure and multiple clinical trials have suggested benefits from coenzyme Q10 (CoQ10) supplementation.