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Assessment and Plan:
Cranberry contains vitamin C and has antioxidant properties for general health promotion but more than 4 ounces per week should be avoided in patients taking warfarin (brand name Coumadin) to avoid potentially prolonging the PTINR.
References:
1.Greenblatt DJ, von Moltke LL, Perloff ES, Luo Y, Harmatz JS, Zinny MA. Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin Pharmacol Ther 2006;79(1):125-33. http://www.ncbi.nlm.nih.gov/pubmed/16413247/?dopt=Abstract . http://www.ncbi.nlm.nih.gov/pubmed/16413247/
2.Paeng CH, Sprague M, Jackevicius CA. Interaction between warfarin and cranberry juice. Clin Ther. 2007 Aug;29(8):1730-5. http://www.clinicaltherapeutics.com/article/S0149-2918(07)00253-6/abstract
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