Hydroxycitric acid (HCA), derived from the Garcinia cambogia fruit and often used to achieve weight loss, failed to provide significant weight reduction or fat mass loss in a group of overweight individuals. For 12-weeks, in addition to following a high-fiber/low-energy diet, participants were administered either 1500 mg/day of HCA (n=66) or placebo (n=69). At the end of the study, participants in both groups lost a significant amount of weight (average loss: -3.2 kg vs -4.1 kg). However, there was no significant difference between the groups for either weight or fat reduction, indicating that HCA had no additional benefit when compared to placebo. (6)
