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Gout Attack Prevention


 

Summary: Gout Attack Prevention

  • Choi HK, et al found the following foods affect the risk of gout attacks (1):
    • The highest quintiles of meat and seafood consumption were associated with a 41% and 51% higher risk of gout attacks respectively.
    • An increased intake of dairy products, (especially low fat) resulted in a 44% lower risk of gout attacks.
    • Interestingly, patients are traditionally taught by physicians to avoid purine rich vegetables, but an intake of vegetables rich in purines was not found to be associated with gout attacks.
    • Vegetable proteins had a reduced risk of gout attacks by 27%, and dairy had a 48% lower risk of gout.
    • Alcohol use and body mass index greater than or equal to 25% each increased the risk of gout beyond any current dietary habits.
  • Richette P and Bardin T. expressed that uric acid levels increase with intake of fructose and animal source purines, but a gout attack risk was found to be significantly lower from vegetable source purines compared to animal source purines (2).
  • Zhang Y, et al found that patients with gout who consumed cherries over a two-day period were shown to have (3):
    • A 35% lower risk of gout attacks compared to those who did not eat the fruit, and the lowest risk of gout attack occurred when patients consumed about 3 servings of cherries within the previous 2 days OR=0.39 (range 0.20–0.77 with 95% CI)
    • Any range of cherry intake from 1 to 4 servings improved the risk of gout.
    • Cherry extract also provided a lower risk of gout attacks.
    • The results also suggested that risk of gout flares was 75% lower when cherry intake was combined with allopurinol.

 

References: Gout Attack Prevention
1.Zhang Y, Neogi T, Chen C, Chaisson C, Hunter DJ, Choi HK. Cherry consumption and decreased risk of recurrent gout attacks. Arthritis Rheum. 2012 Dec;64(12):4004-11. http://www.ncbi.nlm.nih.gov/pubmed/23023818
2.Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G. Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med. 2004 Mar 11;350(11):1093-103. http://www.ncbi.nlm.nih.gov/pubmed/15014182
3.Richette P, Bardin T.Purine-rich foods: an innocent bystander of gout attacks?Ann Rheum Dis. 2012 Sep;71(9):1435-6. doi: 10.1136/annrheumdis-2012-201838. Epub 2012 Jul 17. http://www.ncbi.nlm.nih.gov/pubmed/22805973

 

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