Pelargonium sidoides and hepatotoxicity:
Hepatotoxicity was reported in 13 cases of individuals using Pelargonium sidoides but the patients taking this herb also had been taking other hepatotoxic medications or had other conditions including acute pancreatitis, cholangitis, acute cholecystitis, hepatic contusion, viral hepatitis, and autoimmune hepatitis. (8)
Pelargonium sidoides and coumarin:
It is also possible that the hepatotoxicity was in related to the coumarin content of Pelargonium sidoides (9). Until there is enough safety data determined on the use of the herb and the concentration of coumarin is known, it may be best to avoid the use of Pelargonium sidoides.
