Results of a 4-week study of the effect of vitamin E (800 IU of dl-alpha-tocopherol acetate) on platelet aggregation, blood clotting, and simulated bleeding time in 40 healthy individuals suggests that vitamin E does not affect anticoagulation. Vitamin E supplementation was not associated with any significant change in any of the above mentioned study parameters. (7)
Vitamin E and eye health:
Researchers conducted a randomized, controlled, double-blind trial to determine whether vitamin A or vitamin E, alone or in combination, would stop or slow the progression of retinitis pigmentosa, an eye disease in which there is damage to the retina. A total of 601 patients aged 18-49 years old over where assigned to either 15,000 IU/d of vitamin A, 15,000 IU/d of vitamin A plus 400 IU/d of vitamin E, trace amounts of both vitamins, or 400 IU/d of vitamin E. Findings show that those receiving 15,000 IU/d of vitamin A had on average a slower rate of decline of retinal function than the two groups not receiving this dosage. However, 400 IU/d of vitamin E had a negative impact on the progression of retinitis pigmentosa. (8)
