Caffeine

Caffeine users and insomnia:

Participants in a study by Brown et al which were using caffeine were nearly twice as likely to report difficulty falling asleep (odds ratio [OR]=1.79) as those who did not use caffeine. The use of caffeine-containing nonprescription pain killers (analgesics) was associated with difficulty falling asleep while the use of comparable analgesics without caffeine was not. At the third annual follow-up, 2885 study participants aged 67 to 105 completed a survey that included questions about medication use and sleep problems. Only 5.4% of participants were taking caffeine-containing medications. However, these participants were nearly twice as likely to report difficulty falling asleep (odds ratio [OR]=1.79) as those who did not use caffeine containing-medications. This association persisted after taking into account depression, pain, use of multiple drugs or drugs known to interfere with sleep, and coffee consumption with a reported 60% increased risk of difficulty falling asleep (OR=1.60). (4)