The FDA has allowed nutrition companies to include up to 3 grams of Spirulina per serving in supplements and food products. The FDA has not formally determined Spirulina to be GRAS (Generally Recognized as Safe), but has not had any objections to several companies declaring it to be GRAS. The Dietary Supplements Labels Database recommends a maximum of 7 grams per day.
The DSI-EC recommended that Spirulina products be subject to the following testing standards: 1) Testing for microcystins, a hepatotoxic and carcinogenic substance, should be performed with a limit of under 1 part-per-million. 2) Spirulina should not contain more than 10 micrograms per gram of heavy metals. 3) Spirulina should be evaluated for microbial enumeration which includes cyanobacteria.