Drinking caffeinated coffee with meals may decrease insulin sensitivity, according researchers. Ten healthy men 5 mg/kg of caffeinated coffee one hour before eating a meal (75-g oral glucose load) with either a high glycemic index (Crispex) — comprised of foods that raise blood sugar levels quickly, such as processed carbohydrates — or a low glycemic index meal (All Bran). Caffeinated coffee before a high glycemic index meal resulted in significant insulin sensitivity reduction of 40% compared to decaffeinated coffee before the same meal. Caffeinated coffee prior to a low glycemic index meal led a 29% decrease in insulin sensitivity than the same meal eaten after consuming decaffeinated coffee. (36)
