Liu, J et al performed a Cochrane Database Systematic Review including 4 randomized, double-blind, placebo-controlled trials with 452 patients and determined that coenzyme Q10 at a dose of 1200 mg daily for 16 weeks improved activities of daily living ADLs) as assessed by the Unified Parkinson’s Disease Rating Scale (UPDRS) and Schwab and England scales (a means of assessing ADLs in terms of speed and independence through a percentage figure) (37).
Coenzyme Q10 and exercise:
Coenzyme Q10 and exercise capacity: Rosenfeldt F, et al performed a systematic review of the effects of coenzyme Q10 in physical exercise, hypertension and heart failure. The authors found 6 trials which found that coenzyme Q10 (CoQ10) may improve exercise capacity. However, 5 other different trials showed no benefit of CoQ10 on exercise capacity. (25)