Vitamin C intake and cancer mortality in men:
Loria CM and Klag MJ et al found an association between low blood ascorbate (vitamin C) levels and an increased risk of mortality overall and from cancer, among men. Compared to men with high ascorbate blood concentrations (73.8 micromol/L or greater), men with low ascorbate blood concentrations (less than 28.4 micromol/L) have a 57% increased total mortality risk and a 62% increased mortality risk from cancer. No change in risk of mortality was found among men with ascorbate blood concentrations between 28.4 to 73.8 micromol/L. The vitamin C intake corresponding to the higher risk of mortality in men was less than or equal to 60 mg per day. No link between mortality and ascorbate levels were found among women. (7)