Vitamin C intake and cancer mortality:
Carr and Frei recommended a higher vitamin C intake of 90-100 mg per day to avoid chronic diseases and showed somewhat different findings after reviewing cohort studies. They found that low intake of vitamin C was related to an increase in cancer mortality. They also had a different conclusion than Loria et al in that intake of vitamin C was inversely related to cancer mortality in elderly women but not mortality in men. (21)
Vitamin C and heart disease:
Carr and Frei recommended a higher vitamin C intake of 90-100 mg per day to avoid chronic diseases. They found prospective studies which demonstrated that a low vitamin C poses a higher risk of cardiovascular disease. (21)