Cholesterol, High Cholesterol

Glucomannan at a dose of 1240 mg to 4320 mg per day plus a low-calorie diet (1200 kcal) was more effective than placebo and a low calorie diet for improvement in body weight, total cholesterol, and hunger/satiety (55). Weight loss contributes to improvement of hyperlipidemia. Weight loss over 5 weeks was 3.8–4.4 kg with the doses of glucomannan mentioned above (55)

Glucomannan and a low-calorie diet (1200 kcal) was more effective than placebo and a low calorie diet for improvement in body weight, total cholesterol, and hunger/satiety in a 60-day study that included 30 participants (56).

Guar gum, psyllium, and glucomannan fiber adverse reactions and interactions:

Dry powdered fibers are generally safe when mixed with adequate water or another liquid, but these are not without health risks. At least 8 ounces of fluid is recommended when taking dry fibers such as glucomannan, Konjac root, guar gum, Citrucel, and psyllium (Metamucil). Fibers are natural, but they are not without health risks. Health Canada issued a warning that glucomannan fiber caused choking, obstruction of the throat, esophagus or bowels according to reports when not consumed with adequate amount of fluid (57). The warning also stated that the fiber should not be taken before bed. Fibers may also bind medications and interfere with absorption resulting in a reduction in the desired effect of the medication. Therefore, it may be best to take medications 2 hours before or after the fiber is taken.