The relation between red wine in the form of polyphenolic extracts and risk factors associated with cardiovascular disease was examined in a European project FAIR CT 97 3261. Results from a study of 40 healthy volunteers in Barcelona showed a significant increase in HDL cholesterol levels and a decreased oxidation of LDL cholesterol after red wine consumption (30 g alcohol daily for 4 weeks) as compared to the same amount of alcohol given as spirit such as vodka, whiskey, gin, tequila, and rum. Additionally, according to the authors, a meta-analysis indicated a significant negative relationship between moderate wine drinking of 150-300 ml daily and the risk of cardiovascular events. The study concluded that moderate wine consumption is linked with prevention of cardiovascular disease. (39)
