The effects of dealcoholized red wine (DRW) and regular red wine (RW) on risk factors associated with cardiovascular disease in 45 hypercholesterolemic postmenopausal women were analyzed. Participants were randomized to 400 mL/day of either water, DRW or RW for 6 weeks on a controlled diet following a 4-week washout. At the end of the study period, concentrations of fasting lipids, lipoproteins, insulin and glucose were unaffected by DRW intake. However, chronic consumption of RW significantly decreased LDL cholesterol concentrations by 8% and increased HDL cholesterol concentrations by 17%. In summary, regular consumption of red wine reduces cardiovascular disease risk by improving fasting LDL and HDL levels in hypercholesterolemic postmenopausal women. (40)
