Hypoglycemic (low blood sugar) agents, including insulin and oral agents have no effect on heart rate and blood pressure during rest and exercise. They also have no effect on exercise capacity.
Exercise prescription for serious illnesses:
A prominent credible source for exercise prescription is Thompson et al, American College of Sports Medicine’s (ACSM’s) Guidelines for Exercise Testing and Prescription. (17) Another older but valuable source is Gauer, RL and O’Connor, FG with Department of Family Medicine Uniformed Services University of the Health Sciences, “How To Write An Exercise Prescription.” (15) This can be accessed at: http://www.move.va.gov/download/Resources/CHPPM_How_To_Write_And_Exercise_Prescription.pdf