Coenzyme Q10 in patients with hypertension and coronary artery disease:
Fifty-nine patients who had coronary artery disease and who had been on antihypertensive drugs receive oral administration of either B-complex vitamins or coenzyme Q10 60 mg/d. After 8 weeks of therapy, the coenzyme Q10 group had significantly lower systolic and diastolic blood pressure than the placebo group. HDL cholesterol, vitamins A, C, E and beta-carotene showed a significant increase after use of Q10. B-vitamin complex only increased vitamin C and beta-carotene. (47)
Coenzyme Q10, blood pressure, and cholesterol:
Coenzyme Q10 (CoQ10) may be effective in reducing blood pressure and cholesterol. In this study 26 individuals with high blood pressure were supplemented with CoQ10 at a dose of 50 mg twice daily for 10 weeks. At the end of the treatment with CoQ10, CoQ10 levels increased by 0.94 mcg per ml, systolic blood pressure decreased from an average of 164.5 mmHg to 146.7 mmHg, and diastolic blood pressure decreased from an average of 98.1 mmHg to 86.1 mmHg. Average total cholesterol decreased slightly, from 222 mg/dL to 213 mg/dL, while there was no significant change in HDL cholesterol levels (41.1 mg/dL to 43.1 mg/dL). (48)