Coenzyme Q10 and isolated systolic hypertension:
Burke et al. conducted a 12-week randomized, double-blind, placebo-controlled study, consisting of 46 men and 37 women with isolated systolic hypertension. Participants received a twice-daily administration of 60 mg of oral coenzyme Q10 (CoQ10). Blood pressures were monitored twice weekly. The average reduction in systolic blood pressure (SBP) in the isolated systolic hypertension CoQ10 group after 12 weeks of treatment was 17.8 mm Hg. There were no significant orthostatic changes in SBP (refers to blood pressure change when standing up or stretching) in any of the patients. These findings suggest that CoQ10 may be a safe alternative treatment option for hypertensive individuals. (51)