Oral coenzyme Q10 in chronic heart failure:
Oral coenzyme Q10 (CoQ10) supplementation was analyzed in double-blind trials and was found to have positive clinical and hemodynamic effects including improvement in blood pressure and heart rate, especially in chronic heart failure. Experiments using daily supplements of up to 200 mg CoQ10 for 6-12 months and 100 mg/d for up to 6 years have reported no major adverse effects. (52)
Omega-3 fatty acids and high blood pressure:
Omega-3 fatty acid effectiveness and hypertension: In a meta-analysis of 31 controlled trials (n=1356), treatment with omega-3 (n−3) fatty acids supplementation lowered systolic and diastolic blood pressure in hypertensive patients. Researchers found that fish oil supplementation (mean dose of 5.6 grams/day) lowers systolic blood pressure by an average of 3.4 mm Hg and diastolic pressure by an average of 2.0 mm Hg. The effect was found to be highly dose-dependent with 1 gram/day of fish oil lowering systolic pressure by an average of 0.66 mm Hg and diastolic pressure by an average of 0.35 mm Hg. (53)