Kromhout and colleagues looked at the relationship between fish consumption and coronary heart disease (CHD) in 852 middle-aged men. Dietary information was collected in 1960 and a 20-year follow-up established that 78 men had died from CHD. Researchers found an inverse association between fish intake and CHD mortality. CHD mortality was more than 50% lower among the men who consumed at least 30 grams of fish per day than among those who did not eat fish. In conclusion, eating fish once or twice a week may lower risk of CHD. (10)
Fish oil vs. mustard oil for coronary artery disease:
A 12-month, randomized, placebo-controlled trial examined the effects of fish oil versus mustard oil in 360 patients with suspected acute myocardial infarction (AMI), heart attack. Treatments were administered to all patients approximately 18 hours after symptoms of an acute MI. Patients in group A (n = 122) received fish oil 1.08 g/day orally, group B (n = 120) received mustard oil 2.9 g/day orally, and 118 patients received placebo. Results indicated a reduction in total cardiac events in patients treated with fish oil or mustard oil compared with placebo (24.5% and 28% vs 34.7%; p < 0.01). Nonfatal infarctions also occurred less frequently in patients treated with fish oil or mustard oil compared with placebo (13% and 15% vs 25.4%; p < 0.05); however, total cardiac deaths were not reduced in patients treated with mustard oil or fish oil. When compared with the placebo group, patients treated with fish oil or mustard oil showed a reduction in total angina pectoris (chest pain), cardiac arrhythmias (irregular heartbeat), and left ventricular enlargement. Diene conjugates (signal deterioration of lipids/fats) were reduced in both treatment groups, indicating antioxidant activity. (9)
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